2H-triazolo[4,5-b]pyridine-5-carboxylic acid
CAS No.：
Cat. No.: SC24645
Available on Request
Price on Request
Contact us for pricing, MOQ, and lead time
Product Name :2H-triazolo[4,5-b]pyridine-5-carboxylic acid
Cat. No.: :SC24645
Purity / Specification :—
CAS No. :1216149-55-1
MDL No. :MFCD28664573
Molecular Formula :C6H4N4O2
LogP :0.10
Molecular Weight :164.12
TPSA :91.8
Category :Building Blocks
HSN Code :—
SMILES Code :O=C(O)c1ccc2nn[nH]c2n1
Melting Point :—
InChI Key : :MSDSHMASSBUWGM-UHFFFAOYSA-N
Boiling Point :No data available
Application Note
AI GeneratedGenerated by AI. Verify before use in regulatory documents.
Lipinski & ADMET Properties
Computational estimateLipinski Rule of 5
iMW ≤ 500 Da✓ 164.1 Da
LogP ≤ 5✓ 0.10
HBD ≤ 5✓ 2
HBA ≤ 10✓ 5
Max 1 violation allowed for oral bioavailability.
Drug-likeness Score
i58/100
Moderate — typical building block
Predicted LogP
i0.10log units
Optimal range (0–3)
CNS Permeability
iClark model · J Pharm Sci, 1999
CNS− unlikely
TPSA 91.8Ų · Threshold: <60 CNS+ · 60–90 CNS± · >90 CNS−
Requires experimental confirmation.
⚠ These are computational estimates based on Lipinski & Veber physicochemical rules. They are not validated ADMET predictions and must not be used for clinical, regulatory, or safety decisions. For research use only.